Magnesium plays an essential role in a wide range of fundamental cellular reactions. More than 300 enzymes require magnesium as a cofactor. Complexed with ATP, the main carrier of metabolic energy in the body, magnesium is essential for all biosynthetic processes, glycolysis, formation of c-AMP, energy-dependent membrane transport, trans-mission of genetic code for protein synthesis, and muscle function. Magnesium is well regarded for the roles in plays in maintaining healthy mood, sleep patterns and joint function. Malic acid, sometimes known as the “apple acid,” helps the body make ATP more efficiently. Adenosine triphosphate (ATP) is the body's primary form of energy currency. The hydrolysis of ATP to adenosine diphosphate (ADP) and phosphate is the predominant reaction used to create energy for physiological processes. Thus, generation of ATP is the central goal of energy production. Supplemental malic acid has been shown in research studies to increase the amount of malate in mitochondria, and thus increase the energy production capacity of the cell. Malic acid and magnesium can work in conjunction with one another to support healthy joint and immune function. One study has suggested that the use of malic acid and magnesium supplements could have a beneficial effect on patients with fibromyalgia. More research is required to confirm this finding; however, many practitioners have found it to be useful to support the healthy structure and function of the immune and skeletal systems. Amino acids have many functions in the body. They are the building blocks for all body proteins—structural proteins that build muscle, connective tissues, bones and other structures, and functional proteins in the form of thousands of metabolically active enzymes. Amino acids provide the body with the nitrogen that is essential for growth and maintenance of all tissues and structures. Individuals with fibromyalgia have been shown to be deficient in several key amino acids including methionine, tryptophan, phenylalanine, threonine, and lysine. Supplementation with amino acids can help to regulate mood, support healthy sleep patterns and maintain optimal joint and muscle function. The biological functions of vitamin B 6 (pyridoxine) are accomplished by its coenzyme form, pyridoxal-5- phosphate. Vitamin B6 is involved in amino acid metabolism, especially as it pertains to the central nervous system. In the nervous system, pyridoxal-5- phosphate is needed for synthesis of several neurotransmitters, including serotonin (from tryptophan), taurine, dopamine, norepinephrine, histamine, and gamma-aminobutyric acid (GABA). Many experimental and clinical observations support the fact that dietary ,vitamin B 6 is required to maintain normal nervous system function. This pack has been specially designed by Dr. Rodger Murphree, who has specialized in treating fibromyalgia for over 10 years. Dr. Murphree is a chiropractic physician and the author of 5 books for patients and doctors including “Treating and Beating Fibromyalgia and Chronic Fatigue Syndrome.” Designed for maximum effectiveness, convenience and patient compliance, this comprehensive formula provides the key nutrients often found to be deficient in those with fibromyalgia.