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Douglas Laboratories - COENZYME Q-10 60MG W/LIPOIC
 | Description: COENZYME Q-10 60MG W/LIPOIC Size: 30 |
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Functions:
Alpha-lipoic acid is a nutritional coenzyme that participates in the energy metabolism of proteins, carbohydrates and fats, with a particular role in blood glucose disposal. It is also able to scavenge a number of free radicals.
Alpha-lipoic acid is unique among biological antioxidants, because it is soluble in both water and lipids. This allows it to neutralize free radicals just about everywhere in the body, inside and outside the cells. Due to its unique sulfur-containing structure, alpha-lipoic acid can scavenge several types of free radicals, such as the highly reactive hydroxyl, and singlet oxygen free radicals. It is also capable of suppressing the generation of free radicals in the first place, since alpha-lipoic acid chelates transition metals, such as iron and copper. Because alpha-lipoic acid is involved in so many different antioxidant functions in virtually all body tissues, it has been called the universal antioxidant.
Besides being a universal free radical scavenger, alpha-lipoic acid can also recharge other antioxidant systems throughout the body. As mentioned earlier, it can extend the activity of vitamins C and E. In addition, alpha-lipoic acid can also regenerate glutathione.
Coenzyme Q-10 (or ubiquinone) is an important rate-limiting nutrient that is a cofactor in the mitochondrial electron transport chain, the biochemical pathway in cellular respiration from which adenosine triphosphate (ATP) and metabolic energy is derived. Since nearly all cellular activities are dependent upon energy, coenzyme Q-10 is essential for the health of all human tissues and organs.
Coenzyme Q-10 is a naturally-occurring antioxidant nutrient which retards free radical formation in biological systems. Coenzyme Q-10 resembles vitamin E and vitamin K in chemical structure. Biochemically, it functions much like vitamin E in that it participates in antioxidant and free radical reactions.
Item type:
Other Nutritional Supplements
Indications:
Coenzyme Q-10 with Lipoic Acid may be a useful dietary supplement for individuals wishing to supplement their diet with a more complete antioxidant defense.
Formula:
7362
Suggested usage:
Adults take 1 capsule daily with meals or as directed by physician.
Warnings/Side effects:
No adverse side effects reported.
Storage:
Store in a cool, dry place, away from direct light. Keep out of reach of children.
References:
Ames BN. Micronutrients prevent cancer and delay aging. Toxicol Lett 1998;102-103:5-18. Anuradha B, Varalakshmi P. Activities of glucose-metabolizing enzymes in experimental neurotoxic models with lipoate as an alleviator. J Appl Toxicol 1999;19:405-409. Berkson BM. A conservative triple antioxidant approach to the treatment of hepatitis C. Combination of alpha lipoic acid (thioctic acid), silymarin, and selenium: three case histories [In Process Citation]. Med Klin 1999;94 Suppl 3:84-9. Borcea V, Nourooz-Zadeh J, Wolff SP, Klevesath M, Hofmann M, Urich H, (continued on reverse) Product Data Douglas Laboratories ® Wahl P, Ziegler R, Tritschler H, Halliwell B, Nawroth PP. alpha-Lipoic acid decreases oxidative stress even in diabetic patients with poor glycemic control and albuminuria. Free Radic Biol Med 1999;26:1495-500. Bustamante J, Lodge JK, Marcocci L, Tritschler HJ, Packer L, Rihn BH. Alpha-lipoic acid in liver metabolism and disease. Free Radic Biol Med 1998;24:1023-39. Langsjoen PH, Langsjoen AM. Overview of the use of CoQ10 in cardiovascular disease. Biofactors 1999;9:273-84. Linnane AW, Degli Esposti M, Generowicz M, Luff AR, Nagley P. The universality of bioenergetic disease and amelioration with redox therapy. Biochim Biophys Acta 1995;1271:191-4. Miyake Y, Shouzu A, Nishikawa M, Yonemoto T, Shimizu H, Omoto S, Hayakawa T, Inada M. Effect of treatment with 3- hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on serum coenzyme Q10 in diabetic patients. Arzneimittelforschung 1999;49:324-9. Mortensen SA, Leth A, Agner E, Rohde M. Dose-related decrease of serum coenzyme Q10 during treatment with HMG- CoA reductase inhibitors. Mol Aspects Med 1997;18:S137-44. Niibori K, Yokoyama H, Crestanello JA, Whitman GJ. Acute administration of liposomal coenzyme Q10 increases myocardial tissue levels and improves tolerance to ischemia reperfusion injury. J Surg Res 1998;79:141-5.
Manufactured:
Manufactured by Douglas Laboratories 600 Boyce Road Pittsburgh, PA 15205 800-245-4440
Information:
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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